Saturday, November 29, 2014


Common name: Pariprazole sodium;Rabeprazole sodium;LY-307640;E-3810;Aciphex;Pariet
Trademarks:  AcipHex;Pariet;Acigard;Rabemac;Rabiloz;Rabsiv
Molecular Formula: C18H21N3O3S
CAS Registry Number: 117976-89-3
CAS Name: 2-[[[4-(3-Methoxypropoxy)-3-methyl-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole
Molecular Weight: 359.44
Activity: Anti-Helicobacter Pylori Agents, Antiulcer Drugs, Esophageal Diseases, Gastric Antisecretory Drugs, Gastroesophageal Reflux Disease, GASTROINTESTINAL DRUGS, ABCC3 Expression Enhancers, H+/K+-ATPase Inhibitors

Rabeprazole synthesis: WO2003101452A2

Rabeprazole synthesis: US5045552 (same appears in Drugs Future 1991, 16(1), 19)

1. Souda, S.; et. al. Pyridine derivatives, pharmaceutical compositions. comprising the same, the use of the same for the manufacture of medicaments having therapeutic or preventative value, and a process for preparing the same. US504552US5998445.
2. Castaner, J.; et. al. E-3810. Drugs Fut 1991, 16(1), 19.
3. Meenakshisunderam,S.; et. al. Process for the preparation of highly pure rabeprazole sodium salt. WO2003101452A2

For more drugs and their synthesis: Synayurajan database