Thursday, January 15, 2015


Common name: Ticlopidine; Panaldine; Tiklyd; Tiklid; Ipaton; Ticlodone; Ticlodix; Ticlid; Ticlopidine hydrochloride
Trademarks:  Panaldine; Tiklyd; Tiklid; Ipaton; Ticlodone; Ticlodix; Ticlid
Molecular Formula: C14H14ClNS
CAS Registry Number: 55142-85-3
CAS Name: 5-(2-chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
Molecular Weight: 263.786
Activity: Antiplatelet Therapy; Atherosclerosis Therapy; CARDIOVASCULAR DRUGS; Cerebrovascular Diseases; Coagulation Disorders Therapy; HEMATOLOGIC DRUGS; NEUROLOGIC DRUGS; Stroke; Treatment of; Treatment of Disorders of the Coronary Arteries and Atherosclerosis; P2Y12 (P2T) Antagonists; Adenosine Diphosphate Inhibitor; ADP Inhibitor

Ticlopidine synthesis: Eur J Med Chem 1974, 9(5), 483

Ticlopidine synthesis: JP6388186 (revisited in Ref. 4)

1. Hickey M. J.; et. al. A short expedient synthesis of [(14)C]Ticlopidine. Labelled Comp Radiopharm 2014, 57(3), 172-4.
2. Eloy, F.; et. al. Synthese d thienopyridines et de furopyridines d'interet therapeutique. Eur J Med Chem 1974, 9(5), 483-486.
3. Castaiier, J.; et. al. Ticlopidine. Drugs Fut 1976, 1(4), 190.
4. Al-Shammary, F. J.; et. al. Ticlopidine hydrochloride. Profiles of Drug Substances, Excipients and Related Methodology, Volume 21, 1992.